ADHDgene Database

SNP Report

Basic Info

Name	rs591556 dbSNP Ensembl
Location	Chr11:18061400(Fwd)
Variant Alleles	T/C
Ancestral Allele	T
Functional Annotation	NMD_transcript_variant; intron_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000417164) intron_variant(ENST00000250018; ENST00000341556; ENST00000417164; ENST00000528338)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Johansson S, 2010			logistic regression P-value=0.74, OR=0.96 logistic regression P-value=0.74, OR=0.96	no significant association no significant association	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
TPH1	tryptophan hydroxylase 1	11p15.3-p14	6(2/4/0)

SNPs in LD with rs591556 (count: 9) View in gBrowse (chr11:17945020..18063977 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.


rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]
rs623580	upstream_gene_variant	1(0/1/0)	0.924[YRI]

rs_ID	Functional Annotation	r²[population]
rs10832866	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.936[CEU]
rs6486402	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.936[CEU]; 0.839[CHB]; 0.842[CHD]; 0.832[GIH]; 1.0[JPT]; 0.949[MEX]; 0.957[TSI]
rs536717	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.936[CEU]
rs211102	NMD_transcript_variant; downstream_gene_variant; intron_variant; upstream_gene_variant	0.936[CEU]; 1.0[CHB]; 0.935[CHD]; 0.856[GIH]; 1.0[JPT]; 0.829[LWK]; 1.0[MEX]; 0.913[MKK]; 1.0[TSI]; 0.921[YRI]
rs648228	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.933[CEU]
rs623143	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.936[CEU]; 0.826[TSI]
rs95807	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.936[CEU]; 0.826[TSI]
rs488551	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.936[CEU]