ADHDgene Database

SNP Report

Basic Info

Name	rs5993882 dbSNP Ensembl
Location	Chr22:19937533(Fwd)
Variant Alleles	T/G
Ancestral Allele	T
Functional Annotation	intron_variant; nc_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000467943; ENST00000361682; ENST00000403710; ENST00000407537; ENST00000403184) nc_transcript_variant(ENST00000467943) upstream_gene_variant(ENST00000406520; ENST00000412786; ENST00000207636)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Nyman ES, 2007			No available information. No available information.	No evidence of association was seen. No evidence of association was seen.	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
COMT	catechol-O-methyltransferase	22q11.21	25(5/20/0)

SNPs in LD with rs5993882 (count: 8) View in gBrowse (chr22:19915680..19937533 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.


rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]
rs933271	intron_variant; nc_transcript_variant; upstream_gene_variant	1(0/1/0)	0.887[ASW]; 0.809[CEU]; 0.848[MKK]; 0.804[TSI]

rs_ID	Functional Annotation	r²[population]
rs4485648	intron_variant; nc_transcript_variant	0.823[CHB]; 0.81[JPT]
rs9617850	intron_variant; nc_transcript_variant	0.823[CHB]; 0.81[JPT]
rs7290448	intron_variant; nc_transcript_variant	0.823[CHB]; 0.81[JPT]
rs174674	intron_variant; nc_transcript_variant; upstream_gene_variant	0.94[ASW]; 0.954[LWK]; 0.823[TSI]; 0.962[YRI]
rs7287604	intron_variant; nc_transcript_variant	0.823[CHB]; 0.81[JPT]
rs6518591	intron_variant; nc_transcript_variant; upstream_gene_variant	0.825[ASW]; 0.823[CHB]
rs174675	intron_variant; nc_transcript_variant; upstream_gene_variant	0.941[ASW]; 0.953[LWK]; 0.905[MKK]; 0.802[TSI]; 0.962[YRI]