ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs676643 dbSNP Ensembl
Location	Chr1:23521340(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000374619; ENST00000314113)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Ribases M, 2009(b)			Case-control test: lowest P-value=0.054 for genotype analysi...... Case-control test: lowest P-value=0.054 for genotype analysis, P-value=0.045 for allele analysis in childhood inattentive ADHD. More...	no significance after correcting for multiple comparisons no significance after correcting for multiple comparisons	Significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
HTR1D	5-hydroxytryptamine (serotonin) receptor 1D	1p36.3-p34.3	2(1/1/0)

Genes from other sources (count: 0)

SNPs in LD with rs676643 (count: 32) View in gBrowse (chr1:23354877..23565427 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 1)

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs604030	downstream_gene_variant; intron_variant	1(1/0/0)	1.0[CHB]; 1.0[JPT]

LD-proxies (count: 31)

rs_ID	Functional Annotation	r²[population]
rs588387	upstream_gene_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs643492	intron_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs2806555	intron_variant	0.893[ASW]; 0.93[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.898[MEX]; 0.898[MKK]; 1.0[TSI]; 0.944[YRI]
rs1757042	upstream_gene_variant	0.893[ASW]; 0.933[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.878[MEX]; 0.814[MKK]; 1.0[TSI]; 0.944[YRI]
rs6691404	downstream_gene_variant; intron_variant	0.933[CEU]; 1.0[CHB]; 0.974[CHD]; 1.0[GIH]; 1.0[JPT]; 0.898[MEX]; 0.908[TSI]; 0.829[YRI]
rs1738468		1.0[CHB]; 0.974[CHD]; 1.0[JPT]
rs12087937	intron_variant	0.933[CEU]; 1.0[CHB]; 1.0[JPT]; 0.827[YRI]
rs10799793		0.93[CEU]; 0.947[CHB]; 0.947[CHD]; 0.92[JPT]; 0.868[MKK]; 0.969[TSI]
rs2776815		1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs6695697		0.863[CEU]
rs3845521	downstream_gene_variant; intron_variant	0.805[ASW]; 0.933[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.898[MEX]; 0.908[TSI]; 0.829[YRI]
rs12044504	downstream_gene_variant; intron_variant	0.933[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.898[MEX]; 0.908[TSI]; 0.829[YRI]
rs7548692	intron_variant; nc_transcript_variant	0.947[CHB]; 1.0[JPT]
rs7532266		0.896[CHB]; 0.921[CHD]; 0.92[JPT]
rs10917351	intron_variant; upstream_gene_variant	0.933[CEU]; 1.0[CHB]; 0.974[CHD]; 1.0[GIH]; 1.0[JPT]; 0.898[MEX]; 0.908[TSI]; 0.829[YRI]
rs2746561		0.893[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.898[MEX]; 0.84[MKK]; 1.0[TSI]; 0.944[YRI]
rs1738467	upstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs12038873	intron_variant; upstream_gene_variant	0.933[CEU]; 1.0[CHB]; 0.974[CHD]; 1.0[GIH]; 1.0[JPT]; 0.898[MEX]; 0.908[TSI]; 0.829[YRI]
rs4654837		0.862[CEU]
rs11578046	intron_variant	0.947[CHB]; 1.0[JPT]
rs2806566	upstream_gene_variant	0.893[ASW]; 0.933[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.898[MEX]; 0.84[MKK]; 1.0[TSI]; 0.944[YRI]
rs7543975	downstream_gene_variant; intron_variant; nc_transcript_variant	0.947[CHB]; 0.947[CHD]; 1.0[JPT]
rs2274687	5_prime_UTR_variant; intron_variant; upstream_gene_variant	0.805[ASW]; 0.933[CEU]; 0.947[CHB]; 0.948[CHD]; 0.941[GIH]; 1.0[JPT]; 0.898[MEX]; 0.908[TSI]; 0.829[YRI]
rs623988	3_prime_UTR_variant; intron_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs12067252	intron_variant	0.917[CEU]; 0.927[CHB]
rs10917363		0.805[ASW]; 0.93[CEU]; 0.947[CHB]; 0.947[CHD]; 0.878[GIH]; 0.92[JPT]; 0.898[MEX]; 1.0[TSI]
rs674386	upstream_gene_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs2806570		1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs12027190		0.841[CHB]
rs586589	upstream_gene_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 1.0[MKK]; 1.0[TSI]; 1.0[YRI]
rs641032	downstream_gene_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]