ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs6919857 dbSNP Ensembl
Location	Chr6:137140454(Fwd)
Variant Alleles	C/T
Ancestral Allele	T
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000318471; ENST00000367756; ENST00000541292)
No. of Studies	2 (significant: 0; non-significant: 2; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Neale BM, 2008	C:T		Uncorrected TDT P-value=2.46E-05 (OR=0.749); Corrected TDT P...... Uncorrected TDT P-value=2.46E-05 (OR=0.749); Corrected TDT P-value=4.79E-05 (OR=0.749) More...	One of top 25 results in both uncorrected and corrected TDT ...... One of top 25 results in both uncorrected and corrected TDT test More...	Non-significant
Lantieri F, 2010	C:T		Binomial P-value=0.62, OR=1.03 for whole sample; Binomial P-...... Binomial P-value=0.62, OR=1.03 for whole sample; Binomial P-value=0.55, OR=1.01 for C-subtype More...	no significant association no significant association	Non-significant

SNP related genes (count: 1)

Literature-origin genes (count: 0)

Genes from other sources (count: 1)

Approved Symbol	Approved Name	Location
PEX7	peroxisomal biogenesis factor 7	6q21-q22.2

SNPs in LD with rs6919857 (count: 58) View in gBrowse (chr6:137083138..137243020 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 58)

rs_ID	Functional Annotation	r²[population]
rs9483947	intron_variant	0.882[CEU]; 1.0[JPT]; 0.927[TSI]
rs3734552	intron_variant	0.96[CEU]; 1.0[JPT]; 0.927[TSI]
rs1570054	intron_variant	0.882[CEU]; 1.0[JPT]; 0.902[TSI]
rs3799476	intron_variant	0.815[JPT]
rs9494587	intron_variant	0.861[JPT]
rs9321578	intron_variant	0.882[CEU]; 0.815[JPT]
rs717088	intron_variant; upstream_gene_variant	0.917[CEU]; 0.815[JPT]; 0.855[TSI]
rs9494569	intron_variant	0.882[CEU]; 1.0[JPT]; 0.903[TSI]
rs3903660		0.96[CEU]; 1.0[JPT]; 0.952[TSI]
rs9494579	downstream_gene_variant; intron_variant	0.922[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 0.953[JPT]; 0.903[MEX]; 0.825[TSI]
rs7740484	intron_variant	0.92[ASW]; 0.882[CEU]; 0.801[CHD]; 0.815[JPT]; 0.833[TSI]
rs1884940	intron_variant	0.882[CEU]; 0.815[JPT]
rs6570104	downstream_gene_variant; intron_variant	0.959[CEU]; 0.953[JPT]
rs1998164	upstream_gene_variant	0.918[CEU]; 1.0[CHB]; 1.0[JPT]
rs9321580	intron_variant	0.861[JPT]
rs10223555		0.915[CEU]; 1.0[JPT]
rs9321582	downstream_gene_variant; intron_variant	0.815[JPT]
rs7746446		0.921[CEU]; 1.0[JPT]
rs9399197	intron_variant	0.836[CEU]; 0.815[JPT]
rs2050713	intron_variant	0.861[JPT]
rs9321570	intron_variant	0.882[CEU]; 1.0[JPT]; 0.88[TSI]
rs9402846	intron_variant	0.839[CEU]; 1.0[JPT]
rs9494574		0.907[CEU]; 1.0[JPT]
rs9373174	intron_variant	0.882[CEU]; 0.954[CHB]; 0.882[CHD]; 0.857[JPT]; 0.833[TSI]
rs1342644	intron_variant	0.861[JPT]
rs3757165	upstream_gene_variant	1.0[CEU]; 0.977[GIH]; 1.0[JPT]; 0.813[MEX]; 0.952[TSI]
rs1022690	intron_variant	0.841[CEU]; 1.0[JPT]
rs1321469	upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 0.95[JPT]; 1.0[YRI]
rs1321473	intron_variant	0.882[CEU]; 0.84[CHD]; 0.815[JPT]; 0.851[TSI]
rs1474987	intron_variant	0.839[CEU]; 0.813[JPT]
rs7750251	intron_variant	0.815[JPT]
rs6912539	intron_variant	0.882[CEU]; 0.932[GIH]; 1.0[JPT]; 0.927[TSI]
rs932589	intron_variant	0.802[CEU]; 0.933[GIH]; 1.0[JPT]
rs9494573		0.922[CEU]; 0.815[CHD]; 1.0[JPT]
rs4524621	intron_variant	0.877[CEU]; 1.0[JPT]; 0.927[TSI]
rs7750763	intron_variant	0.806[JPT]
rs9321572		0.922[CEU]; 0.815[CHD]; 1.0[JPT]
rs9321581	intron_variant	0.805[JPT]
rs11154886	feature_truncation; intron_variant	0.841[CEU]; 0.954[GIH]; 1.0[JPT]
rs1884939	intron_variant	0.861[JPT]
rs7764028	intron_variant	0.96[CEU]; 0.886[CHD]; 0.953[JPT]; 0.903[MEX]; 0.976[TSI]
rs927182	intron_variant	0.861[JPT]
rs9494601	upstream_gene_variant	0.815[JPT]
rs9494591	intron_variant	0.861[JPT]
rs9321574		0.881[CEU]; 1.0[CHB]; 1.0[JPT]
rs2327760		0.959[CEU]; 1.0[JPT]
rs9494600	upstream_gene_variant	0.806[JPT]
rs9402850	intron_variant	0.83[CEU]; 0.815[JPT]
rs3757167	upstream_gene_variant	0.922[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.863[MEX]; 0.825[TSI]
rs11154885	intron_variant	1.0[JPT]
rs3757169	upstream_gene_variant	0.878[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.863[MEX]; 0.825[TSI]
rs6936400	intron_variant	0.882[CEU]; 0.815[JPT]
rs6939424	intron_variant	0.802[CEU]; 0.865[CHB]; 0.815[JPT]
rs7746644		0.956[CEU]; 1.0[JPT]
rs9389450	upstream_gene_variant	0.815[JPT]
rs1342645	intron_variant	0.815[CHD]; 0.857[JPT]
rs9402845	intron_variant	0.882[CEU]; 1.0[JPT]
rs2012700	intron_variant; upstream_gene_variant	0.92[ASW]; 0.882[CEU]; 0.801[CHD]; 0.815[JPT]; 0.833[TSI]