ADHDgene Database

SNP Report

Basic Info

Name	rs7657608 dbSNP Ensembl
Location	Chr4:168154181(Fwd)
Variant Alleles	C/T
Ancestral Allele	T
Functional Annotation	NMD_transcript_variant; intron_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000511905; ENST00000507370; ENST00000502821; ENST00000505187; ENST00000515143; ENST00000511226; ENST00000502741; ENST00000507086; ENST00000515316) intron_variant(ENST00000357154; ENST00000504953; ENST00000357545; ENST00000511531; ENST00000502330; ENST00000506886; ENST00000510741; ENST00000511905; ENST00000507370; ENST00000511269; ENST00000512681; ENST00000502821; ENST00000505187; ENST00000512648; ENST00000510403; ENST00000515143; ENST00000511226; ENST00000502741; ENST00000509854; ENST00000507086; ENST00000515316; ENST00000541637; ENST00000506697; ENST00000512042; ENST00000534949; ENST00000535728; ENST00000421836; ENST00000541354)
No. of Studies	2 (significant: 0; non-significant: 2; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Neale BM, 2008	T:C		Uncorrected TDT P-value=3.30E-05 (OR=1.356); Corrected TDT P...... Uncorrected TDT P-value=3.30E-05 (OR=1.356); Corrected TDT P-value=2.96E-05 (OR=1.356) More...	One of top 25 results in both uncorrected and corrected TDT ...... One of top 25 results in both uncorrected and corrected TDT test More...	Non-significant
Lantieri F, 2010	T:C		Binomial P-value=0.84, OR=0.91 for whole sample; Binomial P-...... Binomial P-value=0.84, OR=0.91 for whole sample; Binomial P-value=0.68, OR=0.95 for C-subtype More...	no significant association no significant association	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location
SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3	4q32.3

SNPs in LD with rs7657608 (count: 17) View in gBrowse (chr4:168154181..168204564 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.