ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs864643 dbSNP Ensembl
Location	Chr3:39555580(Fwd)
Variant Alleles	A/G
Ancestral Allele	G
Functional Annotation	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000311042; ENST00000383754) NMD_transcript_variant(ENST00000442631; ENST00000452959; ENST00000424090) downstream_gene_variant(ENST00000420739; ENST00000428261; ENST00000447324; ENST00000415443) intron_variant(ENST00000479860; ENST00000442631; ENST00000396228; ENST00000424090; ENST00000452959) nc_transcript_variant(ENST00000479860)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lesch KP, 2008			ANOVA P-value=1.30E-08, Mean of ranks=4 ANOVA P-value=1.30E-08, Mean of ranks=4	one of the top 30 single SNPs located in gene regions (inclu...... one of the top 30 single SNPs located in gene regions (including 100kb of flanking sequences) ranked according to the mean rank calculated across three statistics; annotated by GWAS Catalog More...	Trend

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
MOBP	myelin-associated oligodendrocyte basic protein	3p21.33	1(0/0/1)

Genes from other sources (count: 0)

SNPs in LD with rs864643 (count: 80) View in gBrowse (chr3:39517031..39592060 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 80)

rs_ID	Functional Annotation	r²[population]
rs661366	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.877[CHB]; 0.884[JPT]; 0.88[YRI]
rs614823	NMD_transcript_variant; intron_variant	0.829[JPT]
rs1417147	NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 0.824[CHD]; 1.0[JPT]; 0.814[MEX]; 1.0[TSI]
rs505176	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant	0.82[ASW]; 0.89[CEU]; 0.939[CHB]; 0.945[CHD]; 0.941[JPT]; 0.969[TSI]; 0.878[YRI]
rs816492	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 0.972[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 1.0[MKK]; 1.0[TSI]; 1.0[YRI]
rs546031	downstream_gene_variant	1.0[CEU]; 0.884[JPT]
rs4129648	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.884[JPT]
rs1708059	NMD_transcript_variant; intron_variant; synonymous_variant; upstream_gene_variant	1.0[CEU]; 0.884[JPT]; 1.0[TSI]
rs1768237	NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 0.868[JPT]
rs634338	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.937[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.971[MKK]; 1.0[YRI]
rs1707972	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.938[CEU]; 0.939[CHB]; 1.0[CHD]; 1.0[GIH]; 0.938[JPT]; 1.0[MEX]; 1.0[TSI]
rs530080		0.942[CEU]
rs587054	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant	0.937[ASW]; 1.0[CEU]; 0.825[CHB]; 0.893[GIH]; 0.829[JPT]; 0.929[LWK]; 0.856[MEX]; 0.972[MKK]; 1.0[TSI]; 0.815[YRI]
rs1708032	NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 1.0[JPT]
rs1768254	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.825[CHB]; 1.0[GIH]; 0.884[JPT]; 0.856[MEX]; 1.0[TSI]
rs704962	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.82[ASW]; 0.89[CEU]; 1.0[CHB]; 0.945[CHD]; 0.901[GIH]; 1.0[JPT]; 0.951[MEX]; 0.97[TSI]; 0.883[YRI]
rs1513218	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.89[JPT]; 0.838[TSI]
rs6599028	NMD_transcript_variant; intron_variant	0.829[JPT]
rs1768127	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.937[ASW]; 1.0[CEU]; 0.942[CHB]; 0.972[CHD]; 0.893[GIH]; 1.0[JPT]; 0.952[LWK]; 1.0[MEX]; 0.972[MKK]; 1.0[TSI]; 1.0[YRI]
rs645488	NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 0.884[JPT]; 1.0[TSI]
rs1707988	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.857[CHB]; 0.871[JPT]; 0.901[YRI]
rs1768134		1.0[CEU]; 0.942[CHB]; 1.0[JPT]; 1.0[YRI]
rs1768267	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.825[CHB]; 0.884[JPT]; 0.887[YRI]
rs2039843	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.89[JPT]; 0.821[MEX]; 0.835[TSI]
rs529839	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant	1.0[CEU]; 0.893[GIH]; 0.884[JPT]; 1.0[TSI]
rs572971	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.937[ASW]; 1.0[CEU]; 0.825[CHB]; 0.841[GIH]; 0.884[JPT]; 0.928[LWK]; 0.902[MEX]; 0.906[MKK]; 1.0[TSI]; 0.887[YRI]
rs1707956	NMD_transcript_variant; intron_variant	0.829[JPT]
rs1707987	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.88[JPT]
rs1768144		0.943[CEU]
rs946409		1.0[CEU]; 0.879[JPT]
rs482495	NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 0.883[JPT]
rs1708057	5_prime_UTR_variant; NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 0.87[JPT]
rs1708056		1.0[CEU]; 0.825[CHB]; 0.858[JPT]; 0.906[YRI]
rs816520	downstream_gene_variant	1.0[CEU]; 0.825[CHB]; 0.876[JPT]; 0.887[YRI]
rs6809442	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.89[JPT]; 0.823[MEX]; 0.838[TSI]
rs535220	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.87[JPT]
rs1513214	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.825[CHB]; 0.884[JPT]; 0.887[YRI]
rs1631776		0.943[CEU]; 0.841[GIH]; 0.855[MEX]; 0.94[TSI]
rs2542	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant	0.937[ASW]; 1.0[CEU]; 0.939[CHB]; 0.972[CHD]; 0.893[GIH]; 1.0[JPT]; 0.952[LWK]; 1.0[MEX]; 0.972[MKK]; 0.969[TSI]; 1.0[YRI]
rs7616236	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.878[CEU]
rs581691	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[ASW]; 1.0[CEU]; 0.825[CHB]; 1.0[GIH]; 0.884[JPT]; 0.975[LWK]; 0.902[MEX]; 1.0[MKK]; 1.0[TSI]; 0.887[YRI]
rs1707968	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.825[CHB]; 0.884[JPT]
rs602527	downstream_gene_variant	1.0[CEU]; 0.825[CHB]; 0.884[JPT]; 0.887[YRI]
rs552724	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant	1.0[CEU]; 0.825[CHB]; 1.0[GIH]; 0.884[JPT]; 0.855[MEX]; 1.0[TSI]
rs1473865	NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 0.824[CHD]; 1.0[JPT]; 0.814[MEX]; 1.0[TSI]
rs569888	downstream_gene_variant	1.0[CEU]; 0.884[JPT]
rs535878	NMD_transcript_variant; intron_variant	0.823[JPT]
rs704963	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.825[CHB]; 1.0[GIH]; 0.884[JPT]; 0.902[MEX]; 0.969[TSI]
rs561543	NMD_transcript_variant; intron_variant	0.921[CEU]
rs816491	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 1.0[MKK]; 1.0[TSI]; 1.0[YRI]
rs11129837		0.813[TSI]
rs538972	NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 0.884[JPT]
rs1708001	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant	0.82[ASW]; 0.89[CEU]; 0.942[CHB]; 0.945[CHD]; 1.0[JPT]; 0.902[MEX]; 0.97[TSI]; 0.842[YRI]
rs1768262	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[ASW]; 1.0[CEU]; 0.825[CHB]; 1.0[GIH]; 0.884[JPT]; 0.975[LWK]; 0.902[MEX]; 1.0[MKK]; 1.0[TSI]; 0.887[YRI]
rs673426	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.884[JPT]
rs574074	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.884[JPT]
rs12490768	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.823[MEX]; 0.838[TSI]
rs1340222	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.825[CHB]; 0.884[JPT]; 0.887[YRI]
rs661422	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.884[JPT]
rs3821372	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.89[JPT]; 0.823[MEX]; 0.838[TSI]
rs1708002	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs1606473		0.823[MEX]; 0.838[TSI]
rs635235		0.943[CEU]
rs1355733	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.825[CHB]; 0.884[JPT]; 0.885[YRI]
rs689352	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.85[CHB]; 0.931[JPT]; 0.903[YRI]
rs1708073	NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 0.884[JPT]
rs1612165	NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CEU]
rs645457	NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CEU]
rs1615046		1.0[CEU]; 0.862[CHB]; 0.935[JPT]
rs1768241	5_prime_UTR_variant; NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 0.884[JPT]
rs1768243	NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 0.879[JPT]
rs614359	NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 0.88[JPT]
rs1708070	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.884[JPT]
rs1398666	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.829[JPT]
rs636476		0.943[CEU]; 0.841[GIH]; 0.941[TSI]
rs3821373	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.89[JPT]
rs1708000	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant	0.89[CEU]; 0.942[CHB]; 1.0[JPT]; 0.883[YRI]
rs1615994		1.0[CEU]; 0.825[CHB]; 0.884[JPT]
rs1068953	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.825[CHB]; 1.0[GIH]; 0.884[JPT]; 0.902[MEX]; 1.0[TSI]
rs1768252	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 0.825[CHB]; 0.884[JPT]