ADHDgene Database

SNP Report

Basic Info

Name	rs880140 dbSNP Ensembl
Location	Chr2:239155732(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000254658; ENST00000254657; ENST00000456601) nc_transcript_variant(ENST00000456601)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Brookes K, 2006	A/G		UNPHASED TDT P-value=0.0285; WHAP TDT P-value=0.202 UNPHASED TDT P-value=0.0285; WHAP TDT P-value=0.202	significant association was observed in UNPHASED analysis significant association was observed in UNPHASED analysis	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
PER2	period homolog 2 (Drosophila)	2q37.3	1(1/0/0)

SNPs in LD with rs880140 (count: 4) View in gBrowse (chr2:239155732..239179914 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs2304676	downstream_gene_variant; intron_variant	1.0[CEU]
rs7570188	intron_variant; upstream_gene_variant	0.818[YRI]
rs3892365	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs744837	intron_variant; nc_transcript_variant; non_coding_exon_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]