ADHDgene Database

SNP Report

Basic Info

Name	rs9332377 dbSNP Ensembl
Location	Chr22:19955692(Fwd)
Variant Alleles	C/T
Ancestral Allele	C
Functional Annotation	NMD_transcript_variant; downstream_gene_variant; intron_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000207636) downstream_gene_variant(ENST00000263207; ENST00000585066; ENST00000401994; ENST00000406259; ENST00000406522; ENST00000403184; ENST00000480792; ENST00000495096; ENST00000428707; ENST00000344269; ENST00000493893) intron_variant(ENST00000412786; ENST00000449653; ENST00000361682; ENST00000407537; ENST00000403710; ENST00000406520; ENST00000207636)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hawi, Z., 2012	C:T	C	P-value=0.7079, X²=0.14, OR=1.07, 95% CI=0.65-1.4...... P-value=0.7079, X²=0.14, OR=1.07, 95% CI=0.65-1.43 More...	The marker did not show significant association with ADHD. The marker did not show significant association with ADHD.	Non-significant

SNP related genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
COMT	catechol-O-methyltransferase	22q11.21	25(5/20/0)
ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome	22q11.21	1(1/0/0)

Approved Symbol	Approved Name	Location
MIR4761	microRNA 4761	22

SNPs in LD with rs9332377 (count: 3) View in gBrowse (chr22:19955692..19991067 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs12485043	intron_variant; nc_transcript_variant; upstream_gene_variant	0.868[CEU]
rs9618725	intron_variant; nc_transcript_variant	0.813[CEU]; 0.841[TSI]
rs9617857	intron_variant; nc_transcript_variant	0.813[CEU]; 0.841[TSI]