ADHDgene Database

SNP Report

Basic Info

Name	rs957795 dbSNP Ensembl
Location	Chr21:46758719(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000445242) nc_transcript_variant(ENST00000416722) non_coding_exon_variant(ENST00000416722)
No. of Studies	2 (significant: 0; non-significant: 2; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lantieri F, 2010	A:G		Binomial P-value=0.98, OR=1.46 for whole sample; Binomial P-...... Binomial P-value=0.98, OR=1.46 for whole sample; Binomial P-value=0.96, OR=1.48 for C-subtype More...	no significant association no significant association	Non-significant
Neale BM, 2008	A:G		Uncorrected TDT P-value=3.86E-05 (OR=0.619) Uncorrected TDT P-value=3.86E-05 (OR=0.619)	One of top 25 results in uncorrected TDT test One of top 25 results in uncorrected TDT test	Non-significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location
LINC00316		21q22.3
NCRNA00316	non-protein coding RNA 316	21q22.3

SNPs in LD with rs957795 (count: 6) View in gBrowse (chr21:46749718..46759886 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs9637167	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs914237		1.0[CEU]
rs9637196	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]
rs957794	downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs9637195	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]
rs2246417	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CHB]