Gene Report
Basic Info
Approved Symbol |
AMACR
|
Symbol Alias |
RACE |
Approved Name |
alpha-methylacyl-CoA racemase |
Location |
5p13.2-q11.1 |
Position |
chr5:33986283-34008220, - |
External Links |
HGNC: 451
Entrez Gene: 23600
Ensembl: ENSG00000242110
UCSC: uc003jig.2
|
No. of Studies |
0 (significant: 0; non-significant: 0; trend: 0) |
Source |
Mapped by significant region |
Gene related studies (count: 0)
Gene related SNPs (count: 0)
Gene related CNVs (count: 0)
Gene related other variant (count: 0)
Gene related regions (count: 1)
Gene related GO terms (count: 11)
Gene related KEGG pathways (count: 3)
ID |
Name |
No. of Genes in ADHDgene |
Brief Description |
hsa00120 |
Primary bile acid biosynthesis |
4 |
Bile acids are steroid carboxylic acids derived from cholest......
Bile acids are steroid carboxylic acids derived from cholesterol in vertebrates. The primary bile acids, cholic acid and chenodeoxycholic acid, are synthesized in the liver and conjugated with taurine or glycine before secretion via bile into the intestine. The conversion from cholesterol to cholic and chenodeoxycholic acids involves four steps: 1) the initiation of synthesis by 7alpha-hydroxylation of sterol precursors, 2) further modifications to the ring structures, 3) side-chain oxidation and shortening (cleavage) by three carbons, and 4) conjugation of the bile acid with taurine or glycine.
More...
|
hsa04146 |
Peroxisome |
9 |
Peroxisomes are essential organelles that play a key role in......
Peroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ether lipids and free radical detoxification. The biogenesis of peroxisomes starts with the early peroxins PEX3, PEX16 and PEX19 and proceeds via several steps. The import of membrane proteins into peroxisomes needs PEX19 for recognition, targeting and insertion via docking at PEX3. Matrix proteins in the cytosol are recognized by peroxisomal targeting signals (PTS) and transported to the docking complex at the peroxisomal membrane. Peroxisomes' deficiencies lead to severe and often fatal inherited peroxisomal disorders (PD). PDs are usually classified in two groups. The first group is disorders of peroxisome biogenesis which include Zellweger syndrome, and the second group is single peroxisomal enzyme deficiencies.
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|
hsa01100 |
Metabolic pathways |
237 |
|
Genes shared at least 5 GO terms with AMACR (count: 2)
Genes shared at least 2 KEGG pathways with AMACR (count: 4)
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