ADHDgene Database

Gene Report

Basic Info

Approved Symbol	DLG2
Symbol Alias	PSD-93, PSD93, chapsyn-110
Approved Name	discs, large homolog 2 (Drosophila)
Previous Name	discs, large homolog 2, chapsyn-110 (Drosophila)
Location	11q21
Position	chr11:83166055-85338966, -
External Links	HGNC: 2901 Entrez Gene: 1740 Ensembl: ENSG00000150672 UCSC: uc001pak.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0004385	guanylate kinase activity	Molecular Function	TAS[8755482]	1
GO:0010923	negative regulation of phosphatase activity	Biological Process	IDA[19389623]	8
GO:0007268	synaptic transmission	Biological Process		96
GO:0005886	plasma membrane	Cellular Component		772
GO:0005515	protein binding	Molecular Function	IPI[15304517]	910
GO:0044224	juxtaparanode region of axon	Cellular Component		2
GO:0030054	cell junction	Cellular Component		77
GO:0019233	sensory perception of pain	Biological Process		17
GO:0014069	postsynaptic density	Cellular Component		23
GO:0045211	postsynaptic membrane	Cellular Component		41

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with DLG2 (count: 8)

Gene Symbol	Pathway Count	Pathway List
GRIN2A	7	synaptic transmission; plasma membrane; protein binding; cell junction; sensory perception of pain; postsynaptic density; postsynaptic membrane;
GRIN2B	6	synaptic transmission; plasma membrane; protein binding; cell junction; postsynaptic density; postsynaptic membrane;
ACHE	5	synaptic transmission; plasma membrane; protein binding; cell junction; postsynaptic membrane;
CHRNA3	5	synaptic transmission; plasma membrane; cell junction; postsynaptic density; postsynaptic membrane;
CHRNA4	5	synaptic transmission; plasma membrane; cell junction; sensory perception of pain; postsynaptic membrane;
ARHGAP32	5	plasma membrane; protein binding; cell junction; postsynaptic density; postsynaptic membrane;
GOPC	5	plasma membrane; protein binding; cell junction; postsynaptic density; postsynaptic membrane;
SHANK2	5	plasma membrane; protein binding; cell junction; postsynaptic density; postsynaptic membrane;

Genes shared at least 2 KEGG pathways with DLG2 (count: 0)

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Region: chr11:83166055..85338966 View in gBrowse