ADHDgene Database

Gene Report

Basic Info

Approved Symbol	EI24
Symbol Alias	PIG8, TP53I8, EPG4
Approved Name	etoposide induced 2.4 mRNA
Name Alias	ectopic P-granules autophagy protein 4 homolog (C. elegans)
Location	11q23
Position	chr11:125439112-125454575, +
External Links	HGNC: 13276 Entrez Gene: 9538 Ensembl: ENSG00000149547 UCSC: uc001qcb.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006915	apoptotic process	Biological Process		111
GO:0006917	induction of apoptosis	Biological Process		31
GO:0005789	endoplasmic reticulum membrane	Cellular Component		140
GO:0006914	autophagy	Biological Process		13
GO:0042493	response to drug	Biological Process		68
GO:0031965	nuclear membrane	Cellular Component		27
GO:0030308	negative regulation of cell growth	Biological Process	IDA[10594026]	21
GO:0016021	integral to membrane	Cellular Component		845

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04115	p53 signaling pathway	14	p53 activation is induced by a number of stress signals, inc...... p53 activation is induced by a number of stress signals, including DNA damage, oxidative stress and activated oncogenes. The p53 protein is employed as a transcriptional activator of p53-regulated genes. This results in three major outputs; cell cycle arrest, cellular senescence or apoptosis. Other p53-regulated gene functions communicate with adjacent cells, repair the damaged DNA or set up positive and negative feedback loops that enhance or attenuate the functions of the p53 protein and integrate these stress responses with other signal transduction pathways. More...

Genes shared at least 5 GO terms with EI24 (count: 0)

Genes shared at least 2 KEGG pathways with EI24 (count: 0)

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Region: chr11:125439112..125454575 View in gBrowse