ADHDgene Database

Gene Report

Basic Info

Approved Symbol	GPR125
Symbol Alias	FLJ38547, PGR21
Approved Name	G protein-coupled receptor 125
Location	4p15.31
Position	chr4:22346694-22517677, -
External Links	HGNC: 13839 Entrez Gene: 166647 Ensembl: ENSG00000152990 UCSC: uc003gqm.1
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Hinney, A., 2011	This GWAS in a small group of clinically ascertained young German patients with ADHD and population-based controls did not reveal genome-wide significant findings. Replication attempts in further German and international samples did also not lead to a P-value(s) below 5E-08.	Non-significant

Gene related SNPs (count: 1)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs7694947	Chr4:22576409(Fwd)		1(0/1/0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 5)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0004930	G-protein coupled receptor activity	Molecular Function		236
GO:0007186	G-protein coupled receptor signaling pathway	Biological Process	TAS[15203201]	72
GO:0007218	neuropeptide signaling pathway	Biological Process		17
GO:0009897	external side of plasma membrane	Cellular Component		34
GO:0016021	integral to membrane	Cellular Component		845

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with GPR125 (count: 0)

Genes shared at least 2 KEGG pathways with GPR125 (count: 0)

View in gBrowse

Region: chr4:22346694..22517677 View in gBrowse