Gene Report
Basic Info
Approved Symbol |
NLRX1
|
Symbol Alias |
NOD9, CLR11.3 |
Approved Name |
NLR family member X1 |
Name Alias |
nucleotide-binding oligomerization domain, leucine rich repeat containing X1, "NOD-like receptor X1", "NLR family, X1" |
Location |
11q23.3 |
Position |
chr11:119037277-119054725, + |
External Links |
HGNC: 29890
Entrez Gene: 79671
Ensembl: ENSG00000160703
UCSC: uc001pvw.2
|
No. of Studies |
0 (significant: 0; non-significant: 0; trend: 0) |
Source |
Mapped by significant region |
Gene related studies (count: 0)
Gene related SNPs (count: 0)
Gene related CNVs (count: 0)
Gene related other variant (count: 0)
Gene related regions (count: 1)
Gene related GO terms (count: 6)
Gene related KEGG pathways (count: 1)
ID |
Name |
No. of Genes in ADHDgene |
Brief Description |
hsa04622 |
RIG-I-like receptor signaling pathway |
10 |
Specific families of pattern recognition receptors are respo......
Specific families of pattern recognition receptors are responsible for detecting viral pathogens and generating innate immune responses. Non-self RNA appearing in a cell as a result of intracellular viral replication is recognized by a family of cytosolic RNA helicases termed RIG-I-like receptors (RLRs). The RLR proteins include RIG-I, MDA5, and LGP2 and are expressed in both immune and nonimmune cells. Upon recognition of viral nucleic acids, RLRs recruit specific intracellular adaptor proteins to initiate signaling pathways that lead to the synthesis of type I interferon and other inflammatory cytokines, which are important for eliminating viruses.
More...
|
Genes shared at least 5 GO terms with NLRX1 (count: 1)
Genes shared at least 2 KEGG pathways with NLRX1 (count: 0)
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