ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SORD
Approved Name	sorbitol dehydrogenase
Location	15q15-q21.1
Position	chr15:45315302-45367287, +
External Links	HGNC: 11184 Entrez Gene: 6652 Ensembl: ENSG00000140263 UCSC: uc001zul.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_170	chr15:43087208-43281530 (NCBI Build 35 (hg17))	194323	15q21.1	Deletion (hemizygous)	Paternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006062	sorbitol catabolic process	Biological Process	IDA[3365415]	1
GO:0006006	glucose metabolic process	Biological Process	TAS[14965227]	19
GO:0016020	membrane	Cellular Component	IDA[8487505]	139
GO:0008270	zinc ion binding	Molecular Function	IDA[12962626]	323
GO:0030317	sperm motility	Biological Process	NAS[16278369]	6
GO:0030246	carbohydrate binding	Molecular Function	NAS[12962626]	28
GO:0031966	mitochondrial membrane	Cellular Component		12
GO:0031514	motile cilium	Cellular Component		8
GO:0005615	extracellular space	Cellular Component	TAS[6177277]	126
GO:0003939	L-iditol 2-dehydrogenase activity	Molecular Function	IDA[3365415]	1
GO:0046370	fructose biosynthetic process	Biological Process	IDA[3365415]	1
GO:0051160	L-xylitol catabolic process	Biological Process	IDA[8487505]	1
GO:0051164	L-xylitol metabolic process	Biological Process	IDA[3365415]	1
GO:0051287	NAD binding	Molecular Function	IDA[12962626]	4

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa01100	Metabolic pathways	237
hsa00051	Fructose and mannose metabolism	11

Genes shared at least 5 GO terms with SORD (count: 0)

Genes shared at least 2 KEGG pathways with SORD (count: 9)

Gene Symbol	Pathway Count	Pathway List
ALDOA	2	Metabolic pathways; Fructose and mannose metabolism;
ALDOB	2	Metabolic pathways; Fructose and mannose metabolism;
FBP1	2	Metabolic pathways; Fructose and mannose metabolism;
FBP2	2	Metabolic pathways; Fructose and mannose metabolism;
GMDS	2	Metabolic pathways; Fructose and mannose metabolism;
GMPPA	2	Metabolic pathways; Fructose and mannose metabolism;
HK1	2	Metabolic pathways; Fructose and mannose metabolism;
HKDC1	2	Metabolic pathways; Fructose and mannose metabolism;
TSTA3	2	Metabolic pathways; Fructose and mannose metabolism;

View in gBrowse

Region: chr15:45315302..45367287 View in gBrowse