ADHDgene Database

SNP Report

Basic Info

Name	rs2114961 dbSNP Ensembl
Location	Chr5:134574232(Fwd)
Variant Alleles	T/G
Ancestral Allele	T
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000432382; ENST00000505663) nc_transcript_variant(ENST00000505663)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hinney, A., 2011		T	GWAS P-value=2.70E-05, OR=1.46, Replication FBAT P-value=1, ...... GWAS P-value=2.70E-05, OR=1.46, Replication FBAT P-value=1, Combination P-value=1.65E-04 More...	This GWAS in a small group of clinically ascertained young G...... This GWAS in a small group of clinically ascertained young German patients with ADHD and population-based controls did not reveal genome-wide significant findings. Replication attempts in further German and international samples did also not lead to a P-value(s) below 5E-08. More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
H2AFY	H2A histone family, member Y	5q31.1	1(0/1/0)

SNPs in LD with rs2114961 (count: 2) View in gBrowse (chr5:134574232..134577757 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs6896456	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[CHD]; 1.0[JPT]
rs7709093	feature_truncation; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]; 0.85[YRI]