ADHDgene Database

SNP Report

Basic Info

Name	rs3793243 dbSNP Ensembl
Location	Chr7:73121347(Fwd)
Variant Alleles	A/G
Ancestral Allele	A
Functional Annotation	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000423166; ENST00000436944) intron_variant(ENST00000395155; ENST00000222812; ENST00000470878; ENST00000395154; ENST00000395156; ENST00000462135) nc_transcript_variant(ENST00000470878; ENST00000462135) upstream_gene_variant(ENST00000461441; ENST00000480126; ENST00000497980; ENST00000496216; ENST00000491427; ENST00000578924; ENST00000494245)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Sanchez-Mora, C., 2012			P-value=0.003, Genotype12+22 vs11: P-value=0.006, OR(95%CI)=...... P-value=0.003, Genotype12+22 vs11: P-value=0.006, OR(95%CI)=1.39(1.10¨C1.77); Genotypes22 vs11+12: P-value=0.006, OR(95%CI)=1.46(1.12¨C1.92); allelic P-value=7.1e-4, OR(95%CI)=1.31(1.12¨C1.53) More...	When adults with ADHD were considered, nominal differences w...... When adults with ADHD were considered, nominal differences were found for nine SNPs located in five genes. After applying a FDR of 15%, only the four SNPs in STX1A remained associated with adulthood ADHD. More...	Significant

SNP related genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
STX1A	syntaxin 1A (brain)	7q11.2	3(2/1/0)

Approved Symbol	Approved Name	Location
WBSCR22	Williams Beuren syndrome chromosome region 22	7q11.23
MIR4284	microRNA 4284	7

SNPs in LD with rs3793243 (count: 2) View in gBrowse (chr7:73092568..73121347 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs4363087	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant; upstream_gene_variant	1(1/0/0)	0.862[CHB]