ADHDgene Database

SNP Report

Basic Info

Name	rs42460 dbSNP Ensembl
Location	Chr16:55737656(Fwd)
Variant Alleles	G/A
Ancestral Allele	A
Functional Annotation	3_prime_UTR_variant; downstream_gene_variant; intron_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000379906; ENST00000567238; ENST00000414754) downstream_gene_variant(ENST00000566163; ENST00000568943) intron_variant(ENST00000219833; ENST00000574918; ENST00000561820)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Kim JW, 2008			X²=0.883, P-value=0.347, OR=1.17 X²=0.883, P-value=0.347, OR=1.17	not associated with ADHD not associated with ADHD	Non-significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	16q12.2	16(10/5/1)
NET1	neuroepithelial cell transforming 1	10p15	0

SNPs in LD with rs42460 (count: 12) View in gBrowse (chr16:55732620..55783706 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs36009	downstream_gene_variant; intron_variant; upstream_gene_variant	3(1/2/0)	0.879[CEU]; 0.837[CHD]; 0.904[GIH]; 0.85[JPT]; 1.0[TSI]
rs1948773		1(0/1/0)	0.867[CHD]; 0.85[JPT]; 0.889[MEX]

rs_ID	Functional Annotation	r²[population]
rs9938863	intron_variant; nc_transcript_variant	0.834[CHD]; 0.889[MEX]
rs13335642	intron_variant; nc_transcript_variant	0.866[YRI]
rs13333562	upstream_gene_variant	0.834[CHD]; 0.85[JPT]; 0.889[MEX]
rs9937399	intron_variant; nc_transcript_variant	0.804[CHD]; 0.889[MEX]
rs36007	intron_variant	0.879[CEU]; 0.85[JPT]
rs9939593	intron_variant; nc_transcript_variant	0.834[CHD]; 0.889[MEX]
rs1807210	intron_variant; nc_transcript_variant	0.831[CHD]; 0.889[MEX]
rs13338546	intron_variant; nc_transcript_variant	0.834[CHD]; 0.889[MEX]
rs17841334	intron_variant; nc_transcript_variant	0.834[CHD]; 0.889[MEX]
rs2397775		0.834[CHD]; 0.85[JPT]; 0.889[MEX]