ADHDgene Database

SNP Report

Basic Info

Name	rs607138 dbSNP Ensembl
Location	Chr6:16749567(Fwd)
Variant Alleles	A/G
Ancestral Allele	G
Functional Annotation	downstream_gene_variant; intron_variant; nc_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000479680) intron_variant(ENST00000483591; ENST00000244769; ENST00000473388; ENST00000495178; ENST00000467008; ENST00000492857; ENST00000483954; ENST00000498374; ENST00000296858; ENST00000436367; ENST00000344707; ENST00000450222) nc_transcript_variant(ENST00000483591; ENST00000473388; ENST00000495178; ENST00000467008; ENST00000492857; ENST00000483954; ENST00000498374)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Neale BM, 2010 (a)	A:G		P-value=1.69E-05 P-value=1.69E-05	one of top 50 hits from the Genome-Wide Attention-Deficit/Hy...... one of top 50 hits from the Genome-Wide Attention-Deficit/Hyperactivity Disorder (ADHD) meta-analysis More...	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ATXN1	ataxin 1	6p23	1(0/0/1)

SNPs in LD with rs607138 (count: 11) View in gBrowse (chr6:16731227..16758112 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs649266	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1(0/0/1)	0.916[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.928[LWK]; 1.0[MEX]; 0.982[MKK]; 1.0[TSI]; 1.0[YRI]

rs_ID	Functional Annotation	r²[population]
rs660586	intron_variant; nc_transcript_variant	0.848[TSI]
rs639621	intron_variant; nc_transcript_variant	0.829[TSI]
rs493352	intron_variant; nc_transcript_variant	0.848[TSI]
rs651702	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs547491	intron_variant; nc_transcript_variant	0.957[CEU]; 0.817[GIH]; 0.95[MEX]; 0.818[TSI]
rs2927	intron_variant; nc_transcript_variant; upstream_gene_variant	0.874[CEU]
rs648411	intron_variant; nc_transcript_variant	0.848[TSI]
rs500803	intron_variant; nc_transcript_variant; upstream_gene_variant	0.916[CEU]; 1.0[CHB]; 0.903[JPT]; 0.914[YRI]
rs492412	intron_variant; nc_transcript_variant	0.848[TSI]
rs1150637	intron_variant; nc_transcript_variant	0.832[CEU]