ADHDgene Database

SNP Report

Basic Info

Name	rs686 dbSNP Ensembl
Location	Chr5:174868700(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	3_prime_UTR_variant.
Consequence to Transcript	3_prime_UTR_variant(ENST00000329144; ENST00000393752)
No. of Studies	2 (significant: 1; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Oades RD, 2008			P-value=0.006978; FDR P-value=0.06978 in additive model for ...... P-value=0.006978; FDR P-value=0.06978 in additive model for cognitive impulsivity; P-value=0.023762; FDR P-value=0.11881 in dominant model for cognitive impulsivity More...	attained nominal significance for an association with cognit...... attained nominal significance for an association with cognitive impulsivity More...	Significant
Nyman ES, 2007			No available information. No available information.	No evidence of association was seen. No evidence of association was seen.	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DRD1	dopamine receptor D1	5q34-q35	8(5/3/0)

SNPs in LD with rs686 (count: 10) View in gBrowse (chr5:174863905..174891621 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs265981	5_prime_UTR_variant; upstream_gene_variant	2(1/1/0)	0.959[CEU]; 1.0[CHB]; 0.956[CHD]; 0.976[GIH]; 1.0[JPT]; 0.977[TSI]
rs4532	5_prime_UTR_variant	1(1/0/0)	0.96[CEU]; 1.0[CHB]; 1.0[CHD]; 0.976[GIH]; 1.0[JPT]; 0.802[MEX]; 0.977[TSI]