SNP |
Allele Change |
Risk Allele |
Statistical Values |
Author Comments |
Result of Statistical Analysis |
rs1051312 |
T/C |
|
allelic P-value=1, X2=0.0 for case-control, P-value=1, X2=0.0 for family-based; genotypic P-value=0.09, X2=4.78 for case-control, P-value=0.32, X2=2.28 for family-based; X2=1.8, TDT P-value=0.18, Relative risk (95% CI)=2.25 (1.0¨C5.22) |
Case-control analysis revealed lack of any significant diffe......
Case-control analysis revealed lack of any significant difference in allelic frequencies between ADHD probands, their parents and controls P>0.05. rs362569 and rs1051312 failed to reveal any preferential transmission.
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|
Non-significant
|
rs3746544 |
T/G |
|
allelic P-value=0.87, X2=0.0 for case-control, P-value=1, X2=0.0 for family-based; genotypic P-value=0.94, X2=0.11 for case-control, P-value=0.83, X2=0.36 for family-based; X2=3.89, TDT P-value=0.05, Relative risk (95% CI)=2.5 (1.3¨C4.9) |
Case-control analysis revealed lack of any significant diffe......
Case-control analysis revealed lack of any significant difference in allelic frequencies between ADHD probands, their parents and controls P>0.05. rs3746544 'T' allele also showed mild over transmission from parents to probands, with a power of 67.6%, primarily due to a bias in maternal transmission. Comparative analysis of all published reports on rs3746544 also revealed statistically significant transmission of rs3746544 'T' allele.
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|
Non-significant
|
rs8636 |
C/T |
|
allelic P-value=0, X2=0.0 for case-control, P-value=0.75, X2=0.1 for family-based; genotypic P-value=0.84, X2=0.35 for case-control, P-value=0.77, X2=0.52 for family-based; X2=4.5, TDT P-value=0.03, Relative risk (95% CI)=2.6 (1.4¨C4.9) |
Case-control analysis revealed lack of any significant diffe......
Case-control analysis revealed lack of any significant difference in allelic frequencies between ADHD probands, their parents and controls P>0.05. Family-based analyses showed over transmission of the derived allele 'C' of rs8636 to ADHD probands.
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|
Significant
|
rs1889189 |
C/T |
|
allelic P-value=0.47, X2=0.52 for case-control, P-value=0.39, X2=0.75 for family-based; genotypic P-value=0.29, X2=2.47 for case-control, P-value=0.13, X2=4.13 for family-based |
Case-control analysis revealed lack of any significant diffe......
Case-control analysis revealed lack of any significant difference in allelic frequencies between ADHD probands, their parents and controls P>0.05.
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|
Non-significant
|
rs362988 |
A/G |
|
allelic P-value=0.31, X2=1.01 for case-control, P-value=0.47, X2=0.52 for family-based; genotypic P-value=0.47, X2=1.49 for case-control, P-value=0.59, X2=1.04 for family-based; X2=1.5, TDT P-value=0.22, Relative risk (95% CI)=0.6 (0.35¨C1.1) |
Case-control analysis revealed lack of any significant diffe......
Case-control analysis revealed lack of any significant difference in allelic frequencies between ADHD probands, their parents and controls P>0.05. rs362988 'G' allele showed a bias in transmission though the difference was statistically insignificant.
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|
Non-significant
|
rs362569 |
C/T |
|
allelic P-value=0.58, X2=0.31 for case-control, P-value=0.46, X2=0.54 for family-based; genotypic P-value=0.05, X2=5.79 for case-control, P-value=0.51, X2=1.33 for family-based; X2=0.87, TDT P-value=0.35, Relative risk (95% CI)=1.5 (0.8¨C3.0) |
Case-control analysis revealed lack of any significant diffe......
Case-control analysis revealed lack of any significant difference in allelic frequencies between ADHD probands, their parents and controls P>0.05. rs362569 and rs1051312 failed to reveal any preferential transmission.
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|
Non-significant
|