Gene Report
Basic Info
Approved Symbol |
GP1BB
|
Symbol Alias |
CD42c |
Approved Name |
glycoprotein Ib (platelet), beta polypeptide |
Location |
22q11.21-q11.23 |
Position |
chr22:19710468-19712297, + |
External Links |
HGNC: 4440
Entrez Gene: 2812
Ensembl: ENSG00000203618
UCSC: uc002zpz.1
|
No. of Studies |
0 (significant: 0; non-significant: 0; trend: 0) |
Source |
Mapped by CNV |
Gene related studies (count: 0)
Gene related SNPs (count: 0)
Gene related CNVs (count: 2)
Gene related other variant (count: 0)
Gene related regions (count: 0)
Gene related GO terms (count: 9)
Gene related KEGG pathways (count: 2)
ID |
Name |
No. of Genes in ADHDgene |
Brief Description |
hsa04640 |
Hematopoietic cell lineage |
13 |
Blood-cell development progresses from a hematopoietic stem ......
Blood-cell development progresses from a hematopoietic stem cell (HSC), which can undergo either self-renewal or differentiation into a multilineage committed progenitor cell: a common lymphoid progenitor (CLP) or a common myeloid progenitor (CMP). A CLP gives rise to the lymphoid lineage of white blood cells or leukocytes-the natural killer (NK) cells and the T and B lymphocytes. A CMP gives rise to the myeloid lineage, which comprises the rest of the leukocytes, the erythrocytes (red blood cells), and the megakaryocytes that produce platelets important in blood clotting. Cells undergoing these differentiation process express a stage- and lineage-specific set of surface markers. Therefore cellular stages are identified by the specific expression patterns of these genes.
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|
hsa04512 |
ECM-receptor interaction |
13 |
The extracellular matrix (ECM) consists of a complex mixture......
The extracellular matrix (ECM) consists of a complex mixture of structural and functional macromolecules and serves an important role in tissue and organ morphogenesis and in the maintenance of cell and tissue structure and function. Specific interactions between cells and the ECM are mediated by transmembrane molecules, mainly integrins and perhaps also proteoglycans, CD36, or other cell-surface-associated components. These interactions lead to a direct or indirect control of cellular activities such as adhesion, migration, differentiation, proliferation, and apoptosis. In addition, integrins function as mechanoreceptors and provide a force-transmitting physical link between the ECM and the cytoskeleton. Integrins are a family of glycosylated, heterodimeric transmembrane adhesion receptors that consist of noncovalently bound alpha- and beta-subunits.
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|
Genes shared at least 5 GO terms with GP1BB (count: 8)
Genes shared at least 2 KEGG pathways with GP1BB (count: 2)
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