Gene Report
Basic Info
Approved Symbol |
MPHOSPH6
|
Symbol Alias |
MPP6 |
Approved Name |
M-phase phosphoprotein 6 |
Location |
16q23.3 |
Position |
chr16:82181767-82203831, - |
External Links |
HGNC: 7214
Entrez Gene: 10200
Ensembl: ENSG00000135698
UCSC: uc002fgw.2
|
No. of Studies |
0 (significant: 0; non-significant: 0; trend: 0) |
Source |
Mapped by significant region |
Gene related studies (count: 0)
Gene related SNPs (count: 0)
Gene related CNVs (count: 0)
Gene related other variant (count: 0)
Gene related regions (count: 1)
Gene related GO terms (count: 9)
Gene related KEGG pathways (count: 1)
ID |
Name |
No. of Genes in ADHDgene |
Brief Description |
hsa03018 |
RNA degradation |
8 |
The correct processing, quality control and turnover of cell......
The correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay exist and both pathways are initiated by poly(A) shortening of the mRNA. In the 5' to 3' pathway, this is followed by decapping which then permits the 5' to 3' exonucleolytic degradation of transcripts. In the 3' to 5' pathway, the exosome, a large multisubunit complex, plays a key role. The exosome exists in archaeal cells, too. In bacteria, endoribonuclease E, a key enzyme involved in RNA decay and processing, organizes a protein complex called degradosome. RNase E or R interacts with the phosphate-dependent exoribonuclease polynucleotide phosphorylase, DEAD-box helicases, and additional factors in the RNA-degrading complex.
More...
|
Genes shared at least 5 GO terms with MPHOSPH6 (count: 13)
Genes shared at least 2 KEGG pathways with MPHOSPH6 (count: 0)
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