ADHDgene Database

Gene Report

Basic Info

Approved Symbol	OSBPL1A
Previous Symbol	OSBPL1B
Symbol Alias	ORP-1, ORP1
Approved Name	oxysterol binding protein-like 1A
Previous Name	oxysterol binding protein-like 1B
Location	18q11.2
Position	chr18:21742008-21977823, -
External Links	HGNC: 16398 Entrez Gene: 114876 Ensembl: ENSG00000141447 UCSC: uc002kve.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
18q11.2-12.3	chr18:19000000-43500000	1 (1/0/0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological Process		14
GO:0016192	vesicle-mediated transport	Biological Process	NAS[11279184]	28
GO:0015485	cholesterol binding	Molecular Function	IDA[17428193]	10
GO:0008203	cholesterol metabolic process	Biological Process	NAS[10588946]	16
GO:0005515	protein binding	Molecular Function	IPI[16176980]	910
GO:0005634	nucleus	Cellular Component		770
GO:0005730	nucleolus	Cellular Component		243
GO:0005543	phospholipid binding	Molecular Function	NAS[11279184]	61
GO:0005622	intracellular	Cellular Component	IC[11279184]	67
GO:0005770	late endosome	Cellular Component	IDA[16176980]	14
GO:0006869	lipid transport	Biological Process		12
GO:0005737	cytoplasm	Cellular Component		690
GO:0005765	lysosomal membrane	Cellular Component		17

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with OSBPL1A (count: 5)

Gene Symbol	Pathway Count	Pathway List
VPS33B	5	vesicle-mediated transport; protein binding; late endosome; cytoplasm; lysosomal membrane;
APOA1	5	cholesterol binding; cholesterol metabolic process; protein binding; nucleus; phospholipid binding;
MAPK1	5	protein binding; nucleus; nucleolus; late endosome; cytoplasm;
SPATA13	5	protein binding; nucleus; nucleolus; phospholipid binding; cytoplasm;
STAP1	5	protein binding; nucleus; nucleolus; phospholipid binding; cytoplasm;

Genes shared at least 2 KEGG pathways with OSBPL1A (count: 0)

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Region: chr18:21742008..21977823 View in gBrowse