ADHDgene Database

SNP Report

Basic Info

Name	rs11030096 dbSNP Ensembl
Location	Chr11:27665543(Fwd)
Variant Alleles	T/C
Ancestral Allele	T
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000530313; ENST00000499008; ENST00000500662; ENST00000502161; ENST00000532965; ENST00000530686; ENST00000501176; ENST00000499568) nc_transcript_variant(ENST00000530313; ENST00000500662; ENST00000499008; ENST00000502161; ENST00000532965; ENST00000530686; ENST00000501176; ENST00000499568)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Ribases M, 2008			genotypic P-value=0.14; genotypic P-value=0.15 in dominant m...... genotypic P-value=0.14; genotypic P-value=0.15 in dominant model; genotypic P-value=0.074 in recessive model; allelic P-value=0.044, OR=1.22 (1-1.49) in Children More...	provided evidence of association with childhood ADHD provided evidence of association with childhood ADHD	Significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
BDNF	brain-derived neurotrophic factor	11p14.1	14(8/6/0)

Approved Symbol	Approved Name	Location
BDNF-AS1	BDNF antisense RNA 1 (non-protein coding)	11p14.1

SNPs in LD with rs11030096 (count: 17) View in gBrowse (chr11:27572337..27746991 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs2049046	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1(0/1/0)	0.959[CEU]
rs11030101	5_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant; upstream_gene_variant	1(1/0/0)	0.96[CEU]; 0.902[JPT]; 1.0[YRI]

rs_ID	Functional Annotation	r²[population]
rs10835210	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.817[CEU]; 0.804[GIH]; 0.952[JPT]; 0.87[LWK]; 0.833[TSI]
rs10835196	intron_variant; nc_transcript_variant; upstream_gene_variant	0.821[CEU]
rs2030324	intron_variant; nc_transcript_variant; upstream_gene_variant	0.959[CEU]
rs10835193	intron_variant; nc_transcript_variant	0.815[CEU]
rs1519479	intron_variant; nc_transcript_variant	1.0[ASW]; 0.924[CEU]; 0.88[CHB]; 0.812[CHD]; 0.974[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 0.813[MKK]; 0.956[TSI]; 1.0[YRI]
rs7931247	intron_variant; nc_transcript_variant; upstream_gene_variant	0.922[CEU]; 0.872[GIH]; 0.89[TSI]
rs11030094	intron_variant; nc_transcript_variant; upstream_gene_variant	0.892[ASW]; 0.88[CHB]; 0.81[CHD]; 0.922[GIH]; 1.0[JPT]; 0.946[MEX]; 0.813[MKK]; 0.806[TSI]
rs10767665	intron_variant; nc_transcript_variant	0.922[CEU]; 0.872[GIH]; 0.913[TSI]
rs11030048	intron_variant; nc_transcript_variant	0.84[CEU]
rs10767652	intron_variant; nc_transcript_variant	0.821[CEU]
rs7103873	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.961[CEU]
rs7934165	intron_variant; nc_transcript_variant	0.922[CEU]; 0.869[GIH]; 0.912[TSI]
rs1519480	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[YRI]
rs2203877	intron_variant; nc_transcript_variant	1.0[ASW]; 1.0[CEU]; 0.88[CHB]; 0.812[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 0.983[MKK]; 1.0[TSI]; 1.0[YRI]
rs11030064	intron_variant; nc_transcript_variant	0.818[CEU]