ADHDgene Database

SNP Report

Basic Info

Name	rs11030101 dbSNP Ensembl
Location	Chr11:27680744(Fwd)
Variant Alleles	A/T
Ancestral Allele	A
Functional Annotation	5_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant; upstream_gene_variant.
Consequence to Transcript	5_prime_UTR_variant(ENST00000525528; ENST00000439476) NMD_transcript_variant(ENST00000530786) downstream_gene_variant(ENST00000532965) intron_variant(ENST00000395986; ENST00000356660; ENST00000584049; ENST00000533246; ENST00000530786; ENST00000530861; ENST00000395978; ENST00000395983; ENST00000533131; ENST00000438929; ENST00000525950; ENST00000532997; ENST00000395981; ENST00000418212; ENST00000314915; ENST00000420794; ENST00000395980) nc_transcript_variant(ENST00000530686; ENST00000500662; ENST00000499008; ENST00000501176; ENST00000502161; ENST00000499568; ENST00000530313; ENST00000584049) non_coding_exon_variant(ENST00000499568; ENST00000530686; ENST00000500662; ENST00000499008; ENST00000501176; ENST00000502161; ENST00000530313) upstream_gene_variant(ENST00000528035)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Cho SC, 2010(a)			allelic P-value=0.96, X² (1df)=0, genotypic P-val...... allelic P-value=0.96, X² (1df)=0, genotypic P-value=0.667, X² (2df)=0.81 in boys; allelic P-value=0.015, X² (1df)=5.87, genotypic P-value=0.035 in girls More...	the A allele and AA genotype were significantly higher in gi...... the A allele and AA genotype were significantly higher in girls with ADHD than in control girls More...	Significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
BDNF	brain-derived neurotrophic factor	11p14.1	14(8/6/0)

Approved Symbol	Approved Name	Location
BDNF-AS1	BDNF antisense RNA 1 (non-protein coding)	11p14.1

SNPs in LD with rs11030101 (count: 12) View in gBrowse (chr11:27659775..27746991 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs2049046	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1(0/1/0)	1.0[CEU]
rs11030096	intron_variant; nc_transcript_variant	1(1/0/0)	0.96[CEU]; 0.902[JPT]; 1.0[YRI]

rs_ID	Functional Annotation	r²[population]
rs10835210	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.846[CEU]; 0.93[CHB]; 0.952[JPT]
rs1519479	intron_variant; nc_transcript_variant	0.885[CEU]; 0.818[CHB]; 0.902[JPT]; 1.0[YRI]
rs11030094	intron_variant; nc_transcript_variant; upstream_gene_variant	0.818[CHB]; 0.902[JPT]
rs7103873	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]
rs7931247	intron_variant; nc_transcript_variant; upstream_gene_variant	0.96[CEU]
rs1519480	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[YRI]
rs7934165	intron_variant; nc_transcript_variant	0.96[CEU]
rs2030324	intron_variant; nc_transcript_variant; upstream_gene_variant	0.96[CEU]
rs2203877	intron_variant; nc_transcript_variant	0.96[CEU]; 0.818[CHB]; 0.902[JPT]; 1.0[YRI]
rs10767665	intron_variant; nc_transcript_variant	0.96[CEU]