ADHDgene Database

Gene Report

Basic Info

Approved Symbol	FABP6
Symbol Alias	I-15P, ILLBP, I-BAP, ILBP3, I-BABP, ILBP, I-BALB
Approved Name	fatty acid binding protein 6, ileal
Name Alias	illeal lipid-binding protein, "ileal bile acid binding protein", "gastrotropin"
Location	5q23-q35
Position	chr5:159614374-159665742, +
External Links	HGNC: 3561 Entrez Gene: 2172 Ensembl: ENSG00000170231 UCSC: uc003lxx.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
5q33.3	chr5:155700000-159900000	1 (1/0/0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0008289	lipid binding	Molecular Function		23
GO:0015721	bile acid and bile salt transport	Biological Process		4
GO:0008206	bile acid metabolic process	Biological Process		8
GO:0008285	negative regulation of cell proliferation	Biological Process	TAS[9250612]	59
GO:0005829	cytosol	Cellular Component		447
GO:0006629	lipid metabolic process	Biological Process	NAS[9250612]	51
GO:0005737	cytoplasm	Cellular Component	TAS[7588781]	690
GO:0005794	Golgi apparatus	Cellular Component		157
GO:0005634	nucleus	Cellular Component		770
GO:0005215	transporter activity	Molecular Function		41
GO:0044281	small molecule metabolic process	Biological Process		248

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa03320	PPAR signaling pathway	12	Peroxisome proliferator-activated receptors (PPARs) are nucl...... Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that are activated by fatty acids and their derivatives. PPAR has three subtypes (PPARalpha, beta/delta, and gamma) showing different expression patterns in vertebrates. Each of them is encoded in a separate gene and binds fatty acids and eicosanoids. PPARalpha plays a role in the clearance of circulating or cellular lipids via the regulation of gene expression involved in lipid metabolism in liver and skeletal muscle. PPARbeta/delta is involved in lipid oxidation and cell proliferation. PPARgamma promotes adipocyte differentiation to enhance blood glucose uptake. More...

Genes shared at least 5 GO terms with FABP6 (count: 6)

Gene Symbol	Pathway Count	Pathway List
FABP7	5	lipid binding; negative regulation of cell proliferation; cytoplasm; nucleus; transporter activity;
INPPL1	5	negative regulation of cell proliferation; cytosol; cytoplasm; Golgi apparatus; small molecule metabolic process;
CUBN	5	cytosol; lipid metabolic process; Golgi apparatus; transporter activity; small molecule metabolic process;
NAPRT1	5	cytosol; cytoplasm; Golgi apparatus; nucleus; small molecule metabolic process;
PPP1CA	5	cytosol; lipid metabolic process; cytoplasm; nucleus; small molecule metabolic process;
PRKD1	5	cytosol; cytoplasm; Golgi apparatus; nucleus; small molecule metabolic process;

Genes shared at least 2 KEGG pathways with FABP6 (count: 0)

View in gBrowse

Region: chr5:159614374..159665742 View in gBrowse