ADHDgene Database

Gene Report

Basic Info

Approved Symbol	INPP5A
Symbol Alias	5PTASE
Approved Name	inositol polyphosphate-5-phosphatase, 40kDa
Previous Name	inositol polyphosphate-5-phosphatase, 40kD
Name Alias	CTCL tumor antigen HD-CL-02, "43 kDa inositol polyphosphate 5-phophatase", "inositol polyphosphate 5-phophatase, 40kDa", "InsP3 5-phosphatase", "type I inositol-1,4,5-trisphosphate 5-phosphatase"
Location	10q26.3
Position	chr10:134351324-134596984, +
External Links	HGNC: 6076 Entrez Gene: 3632 Ensembl: ENSG00000068383 UCSC: uc001llp.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Jarick[2012]_23	chr10:132453545-135284293 (NCBI36 / hg18)	2830749	10q26.3	del

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0052659	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	Molecular Function		1
GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity	Molecular Function		1
GO:0046854	phosphatidylinositol phosphorylation	Biological Process		5
GO:0042731	PH domain binding	Molecular Function	IPI[8999861]	2
GO:0016020	membrane	Cellular Component	NAS[8006039]	139
GO:0007154	cell communication	Biological Process		10
GO:0004445	inositol-polyphosphate 5-phosphatase activity	Molecular Function	NAS[8006039]	2

Gene related KEGG pathways (count: 3)

ID	Name	No. of Genes in ADHDgene
hsa01100	Metabolic pathways	237
hsa00562	Inositol phosphate metabolism	14
hsa04070	Phosphatidylinositol signaling system	19

Genes shared at least 5 GO terms with INPP5A (count: 0)

Genes shared at least 2 KEGG pathways with INPP5A (count: 14)

Gene Symbol	Pathway Count	Pathway List
CDIPT	3	Metabolic pathways; Inositol phosphate metabolism; Phosphatidylinositol signaling system;
INPPL1	3	Metabolic pathways; Inositol phosphate metabolism; Phosphatidylinositol signaling system;
IPPK	3	Metabolic pathways; Inositol phosphate metabolism; Phosphatidylinositol signaling system;
PI4K2B	3	Metabolic pathways; Inositol phosphate metabolism; Phosphatidylinositol signaling system;
PI4KA	3	Metabolic pathways; Inositol phosphate metabolism; Phosphatidylinositol signaling system;
PIK3C3	3	Metabolic pathways; Inositol phosphate metabolism; Phosphatidylinositol signaling system;
PLCB2	3	Metabolic pathways; Inositol phosphate metabolism; Phosphatidylinositol signaling system;
PLCB3	3	Metabolic pathways; Inositol phosphate metabolism; Phosphatidylinositol signaling system;
PLCD1	3	Metabolic pathways; Inositol phosphate metabolism; Phosphatidylinositol signaling system;
PLCD4	3	Metabolic pathways; Inositol phosphate metabolism; Phosphatidylinositol signaling system;
PLCE1	3	Metabolic pathways; Inositol phosphate metabolism; Phosphatidylinositol signaling system;
PLCG2	3	Metabolic pathways; Inositol phosphate metabolism; Phosphatidylinositol signaling system;
DGKH	2	Metabolic pathways; Phosphatidylinositol signaling system;
PIK3CG	2	Inositol phosphate metabolism; Phosphatidylinositol signaling system;

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Region: chr10:134351324..134596984 View in gBrowse