KEGG Pathway Report
Basic Info
ID |
hsa03320
|
Name |
PPAR signaling pathway |
Description |
Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that are activated by fatty acids and their derivatives. PPAR has three subtypes (PPARalpha, beta/delta, and gamma) showing different expression patterns in vertebrates. Each of them is encoded in a separate gene and binds fatty acids and eicosanoids. PPARalpha plays a role in the clearance of circulating or cellular lipids via the regulation of gene expression involved in lipid metabolism in liver and skeletal muscle. PPARbeta/delta is involved in lipid oxidation and cell proliferation. PPARgamma promotes adipocyte differentiation to enhance blood glucose uptake. |
No. of Genes in ADHDgene |
12 |
Source |
Pathway by Database Search
|
Pathway related genes in ADHDgene (count: 12)