ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	MMP20
Approved Name	matrix metallopeptidase 20
Previous Name	matrix metalloproteinase 20 (enamelysin)
Name Alias	enamelysin
Location	11q22.3
Position	chr11:102447566-102496063, -
External Links	HGNC: 7167 Entrez Gene: 9313 Ensembl: ENSG00000137674 UCSC: uc001phc.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)
11q22	chr11:97200000-110400000	1 (1/0/0)

Gene related GO terms (count: 9)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0070173	regulation of enamel mineralization	Biological Process	TAS[18434575]	1
GO:0097186	amelogenesis	Biological Process		1
GO:0004222	metalloendopeptidase activity	Molecular Function		33
GO:0005509	calcium ion binding	Molecular Function		124
GO:0005515	protein binding	Molecular Function	IPI[18434575]	910
GO:0005578	proteinaceous extracellular matrix	Cellular Component		47
GO:0005615	extracellular space	Cellular Component	TAS[9398237]	126
GO:0006508	proteolysis	Biological Process		102
GO:0008270	zinc ion binding	Molecular Function		323

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with MMP20 (count: 12)

Gene Symbol	Pathway Count	Pathway List
MMP10	6	metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix; extracellular space; proteolysis; zinc ion binding;
MMP13	6	metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix; extracellular space; proteolysis; zinc ion binding;
MMP3	6	metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix; extracellular space; proteolysis; zinc ion binding;
MMP8	6	metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix; extracellular space; proteolysis; zinc ion binding;
ADAM8	5	metalloendopeptidase activity; calcium ion binding; protein binding; proteolysis; zinc ion binding;
MMP1	5	metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix; proteolysis; zinc ion binding;
MMP11	5	metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix; proteolysis; zinc ion binding;
MMP12	5	metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix; proteolysis; zinc ion binding;
MMP16	5	metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix; proteolysis; zinc ion binding;
MMP24	5	metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix; proteolysis; zinc ion binding;
MMP27	5	metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix; proteolysis; zinc ion binding;
MMP7	5	metalloendopeptidase activity; proteinaceous extracellular matrix; extracellular space; proteolysis; zinc ion binding;

Genes shared at least 2 KEGG pathways with MMP20 (count: 0)

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Region: chr11:102447566..102496063 View in gBrowse