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- Data Summary
Gene Report
Approved Symbol | TRIP12 |
---|---|
Symbol Alias | KIAA0045 |
Approved Name | thyroid hormone receptor interactor 12 |
Location | 2q36.3 |
Position | chr2:230631930-230787955, - |
External Links |
HGNC: 12306 Entrez Gene: 9320 Ensembl: ENSG00000153827 UCSC: uc002vpw.1 |
No. of Studies | 0 (significant: 0; non-significant: 0; trend: 0) |
Source | Mapped by PBA pathway |
GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)
ID | Name | Type | Evidence[PMID] | No. of Genes in ADHDgene |
---|---|---|---|---|
GO:0035257 | nuclear hormone receptor binding | Molecular Function | 30 |
GO terms by database search (count: 14)
ID | Name | No. of Genes in ADHDgene | Brief Description |
---|---|---|---|
hsa04120 | Ubiquitin mediated proteolysis | 29 | Protein ubiquitination plays an important role in eukaryotic...... Protein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to proteins being degraded is performed by a reaction cascade consisting of three enzymes, named E1 (ubiquitin activating enzyme), E2 (ubiquitin conjugating enzyme), and E3 (ubiquitin ligase). Each E3 has specificity to its substrate, or proteins to be targeted by ubiquitination. Many E3s are discovered in eukaryotes and they are classified into four types: HECT type, U-box type, single RING-finger type, and multi-subunit RING-finger type. Multi-subunit RING-finger E3s are exemplified by cullin-Rbx E3s and APC/C. They consist of a RING-finger-containing subunit (RBX1 or RBX2) that functions to bind E2s, a scaffold-like cullin molecule, adaptor proteins, and a target recognizing subunit that binds substrates. More... |
Region: chr2:230631930..230787955 View in gBrowse
Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014