ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	UXT
Symbol Alias	ART-27
Approved Name	ubiquitously-expressed transcript
Location	Xp11.23-p11.22
Position	chrX:47511195-47518560, -
External Links	HGNC: 12641 Entrez Gene: 8409 Ensembl: ENSG00000126756 UCSC: uc004dim.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 18)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000226	microtubule cytoskeleton organization	Biological Process	IMP[16221885]	39

GO terms by database search (count: 17)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006457	protein folding	Biological Process		28
GO:0008017	microtubule binding	Molecular Function	TAS[12762840]	32
GO:0005813	centrosome	Cellular Component	IDA[16221885]	71
GO:0005856	cytoskeleton	Cellular Component	IDA[12762840]	54
GO:0048487	beta-tubulin binding	Molecular Function	IDA[12762840]	4
GO:0051015	actin filament binding	Molecular Function	IDA[12762840]	14
GO:0016272	prefoldin complex	Cellular Component		1
GO:0047497	mitochondrion transport along microtubule	Biological Process	TAS[12762840]	4
GO:0051082	unfolded protein binding	Molecular Function		19
GO:0051297	centrosome organization	Biological Process	IMP[16221885]	5
GO:0001106	RNA polymerase II transcription corepressor activity	Molecular Function		3
GO:0000930	gamma-tubulin complex	Cellular Component	IDA[16221885]	3
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process		78
GO:0005737	cytoplasm	Cellular Component		690
GO:0005634	nucleus	Cellular Component	IDA[12762840]	770
GO:0005515	protein binding	Molecular Function	IPI[17635584]	910
GO:0003682	chromatin binding	Molecular Function		48

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with UXT (count: 21)

Gene Symbol	Pathway Count	Pathway List
CDK5RAP2	7	microtubule binding; centrosome; cytoskeleton; centrosome organization; microtubule cytoskeleton organization; cytoplasm; protein binding;
MAP1S	7	microtubule binding; beta-tubulin binding; actin filament binding; mitochondrion transport along microtubule; microtubule cytoskeleton organization; nucleus; protein binding;
TFAP2A	7	centrosome; RNA polymerase II transcription corepressor activity; negative regulation of transcription from RNA polymerase II promoter; cytoplasm; nucleus; protein binding; chromatin binding;
CRYAB	6	protein folding; microtubule binding; unfolded protein binding; cytoplasm; nucleus; protein binding;
APC	6	microtubule binding; centrosome; microtubule cytoskeleton organization; cytoplasm; nucleus; protein binding;
PAFAH1B1	6	microtubule binding; centrosome; microtubule cytoskeleton organization; cytoplasm; nucleus; protein binding;
PLK1	6	microtubule binding; centrosome; centrosome organization; negative regulation of transcription from RNA polymerase II promoter; nucleus; protein binding;
CEP57	5	microtubule binding; centrosome; cytoplasm; nucleus; protein binding;
HOOK3	5	microtubule binding; centrosome; microtubule cytoskeleton organization; cytoplasm; protein binding;
KIF23	5	microtubule binding; centrosome; microtubule cytoskeleton organization; nucleus; protein binding;
PRC1	5	microtubule binding; microtubule cytoskeleton organization; cytoplasm; nucleus; protein binding;
SNCA	5	microtubule binding; beta-tubulin binding; cytoplasm; nucleus; protein binding;
TPPP	5	microtubule binding; microtubule cytoskeleton organization; cytoplasm; nucleus; protein binding;
CKAP5	5	centrosome; centrosome organization; gamma-tubulin complex; microtubule cytoskeleton organization; protein binding;
PPP4C	5	centrosome; microtubule cytoskeleton organization; cytoplasm; nucleus; protein binding;
TUBG1	5	centrosome; gamma-tubulin complex; microtubule cytoskeleton organization; cytoplasm; protein binding;
RCC1	5	microtubule cytoskeleton organization; cytoplasm; nucleus; protein binding; chromatin binding;
SMC1A	5	microtubule cytoskeleton organization; cytoplasm; nucleus; protein binding; chromatin binding;
SMC3	5	microtubule cytoskeleton organization; cytoplasm; nucleus; protein binding; chromatin binding;
MEN1	5	negative regulation of transcription from RNA polymerase II promoter; cytoplasm; nucleus; protein binding; chromatin binding;
NCOR1	5	negative regulation of transcription from RNA polymerase II promoter; cytoplasm; nucleus; protein binding; chromatin binding;

Genes shared at least 2 KEGG pathways with UXT (count: 0)

View in gBrowse

Region: chrX:47511195..47518560 View in gBrowse