ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	KIF22
Previous Symbol	KNSL4
Symbol Alias	Kid, OBP-1, OBP-2
Approved Name	kinesin family member 22
Previous Name	kinesin-like 4
Location	16p11.2
Position	chr16:29802041-29816706, +
External Links	HGNC: 6391 Entrez Gene: 3835 Ensembl: ENSG00000079616 UCSC: uc002dts.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 2)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_34	chr16:29342178-31155425 (NCBI Build 36.1 (hg18))	1813248	16p11.2	Loss	De novo
CNV_Jarick[2012]_35	chr16:29554843-30085308 (NCBI36 / hg18)	530466	16p11.2	del

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 17)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 17)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0007596	blood coagulation	Biological Process		83
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological Process		14
GO:0003677	DNA binding	Molecular Function		220
GO:0000785	chromatin	Cellular Component		13
GO:0000776	kinetochore	Cellular Component	TAS[8599929]	15
GO:0005737	cytoplasm	Cellular Component		690
GO:0005634	nucleus	Cellular Component		770
GO:0005524	ATP binding	Molecular Function		228
GO:0003777	microtubule motor activity	Molecular Function		17
GO:0005875	microtubule associated complex	Cellular Component		13
GO:0005874	microtubule	Cellular Component		52
GO:0005829	cytosol	Cellular Component		447
GO:0005819	spindle	Cellular Component		29
GO:0007067	mitosis	Biological Process	TAS[8599929]	39
GO:0007018	microtubule-based movement	Biological Process		20
GO:0006281	DNA repair	Biological Process		62
GO:0005925	focal adhesion	Cellular Component		26

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with KIF22 (count: 29)

Gene Symbol	Pathway Count	Pathway List
KIF11	10	blood coagulation; antigen processing and presentation of exogenous peptide antigen via MHC class II; cytoplasm; ATP binding; microtubule motor activity; microtubule; cytosol; spindle; mitosis; microtubule-based movement;
KIF23	9	blood coagulation; antigen processing and presentation of exogenous peptide antigen via MHC class II; nucleus; ATP binding; microtubule motor activity; microtubule; cytosol; spindle; microtubule-based movement;
KIF2C	9	blood coagulation; antigen processing and presentation of exogenous peptide antigen via MHC class II; kinetochore; nucleus; ATP binding; microtubule motor activity; cytosol; mitosis; microtubule-based movement;
KIFC1	8	blood coagulation; nucleus; ATP binding; microtubule motor activity; microtubule associated complex; microtubule; spindle; microtubule-based movement;
MAPK1	8	blood coagulation; DNA binding; cytoplasm; nucleus; ATP binding; cytosol; spindle; focal adhesion;
SMC3	7	chromatin; cytoplasm; nucleus; ATP binding; microtubule motor activity; mitosis; DNA repair;
KLC2	6	blood coagulation; antigen processing and presentation of exogenous peptide antigen via MHC class II; microtubule motor activity; microtubule; cytosol; microtubule-based movement;
DYNC2H1	6	antigen processing and presentation of exogenous peptide antigen via MHC class II; ATP binding; microtubule motor activity; microtubule; cytosol; microtubule-based movement;
MAP1S	6	DNA binding; nucleus; microtubule associated complex; microtubule; cytosol; spindle;
PLK1	6	kinetochore; nucleus; ATP binding; cytosol; spindle; mitosis;
SMC1A	6	kinetochore; cytoplasm; nucleus; ATP binding; microtubule motor activity; DNA repair;
KIF12	6	cytoplasm; ATP binding; microtubule motor activity; microtubule associated complex; microtubule; microtubule-based movement;
ARRB1	5	blood coagulation; chromatin; cytoplasm; nucleus; cytosol;
MAPK3	5	blood coagulation; nucleus; ATP binding; cytosol; focal adhesion;
PRKCB	5	blood coagulation; cytoplasm; nucleus; ATP binding; cytosol;
CENPC1	5	DNA binding; kinetochore; cytoplasm; nucleus; cytosol;
CHD1L	5	DNA binding; cytoplasm; nucleus; ATP binding; DNA repair;
IGHMBP2	5	DNA binding; cytoplasm; nucleus; ATP binding; DNA repair;
PRPF19	5	DNA binding; cytoplasm; nucleus; spindle; DNA repair;
XRCC5	5	DNA binding; cytoplasm; nucleus; ATP binding; DNA repair;
CHEK1	5	chromatin; nucleus; ATP binding; cytosol; DNA repair;
MEN1	5	chromatin; cytoplasm; nucleus; cytosol; DNA repair;
PAFAH1B1	5	kinetochore; cytoplasm; nucleus; microtubule associated complex; cytosol;
CEP164	5	cytoplasm; nucleus; cytosol; mitosis; DNA repair;
KIF19	5	cytoplasm; ATP binding; microtubule associated complex; microtubule; microtubule-based movement;
NEK6	5	cytoplasm; nucleus; ATP binding; microtubule; mitosis;
PTTG1	5	cytoplasm; nucleus; cytosol; mitosis; DNA repair;
SMG1	5	cytoplasm; nucleus; ATP binding; cytosol; DNA repair;
KIF1C	5	ATP binding; microtubule motor activity; microtubule associated complex; microtubule; microtubule-based movement;

Genes shared at least 2 KEGG pathways with KIF22 (count: 0)

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Region: chr16:29802041..29816706 View in gBrowse